Protonix vs. Aciphex

• Are Protonix and Aciphex the Same Thing?
• What Are Possible Side Effects of Protonix?
• What Are Possible Side Effects of Aciphex?
• What Is Protonix?
• What Is Aciphex?
• What drugs interact with Protonix?
• What drugs interact with Aciphex?
• How Should Protonix Be Taken?
• How Should Aciphex Be Taken?

Protonix(pantoprazolesodium) andAciphex(rabeprazolesodium) are proton pump inhibitors (PPIs) used to treatgastroesophageal refluxdisease(GERD) and erosiveesophagitis.

Side effectsof Protonix include:

• injection site reactions (redness,pain, swelling),
• headache,
• nausea,
• vomiting,
• abdominalorstomachpain,
• diarrhea,
• gas,
• dizziness,
• jointpain,
• weight changes,
• drowsiness,
• tiredfeeling, or
• sleepproblems (insomnia).

Common side effects of Aciphex include:

• rashoritching,
• upset stomach,
• diarrhea,
• gas,
• sore throat,
• headache,
• insomnia, or
• nervousness.

Serious side effects of Aciphex include:

• hepatitis,
• abnormalbrainfunction or structure (encephalopathy),
• dizziness,
• swelling,
• joint pain, and
• musclepains.

What is Protonix?

Protonix IV(pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) ofgastroesophagealreflux疾病(GERD)和腐蚀性esophagiti的历史sinadult patients.

What is Aciphex?

Aciphex (rabeprazole sodium) is a proton pump inhibitor (PPI) to reduce stomach acid and is used for the treatment of gastroesophageal reflux disease (GERD),duodenalulcers, and used in combination with antibiotics to treatHelicobacter pylori(H. pylori)bacterialinfections in the stomach.

Protonix may interact with atazanavir,bloodthinners,digoxin,diuretics(waterpills),ketoconazole, ormethotrexate.

Protonix may also interact with nelfinavir,ampicillin, oriron.

Aciphex may interact with atazanavir, blood thinners, digoxin, diuretics (water pills), ketoconazole, or methotrexate.

Aciphex may also interact withcyclosporine.

The recommended adult dose of Protonix is 40mgonce daily.

• ProtonixOralSuspension should be taken 30 minutes before a meal
• Protonix Oral Suspension should only be taken with applesauce or apple juice 30 minutes before a meal.
• Protonix Oral Suspension should not be taken in or with water or other liquids, or with other foods.
• Protonix Oral Suspension should not be chewed or crushed.
• Protonix Oral Suspension packet should not be divided to make a smaller dose.

• Take Aciphex exactly as prescribed. Yourdoctorwill prescribe the dose that is right for you and your medicalcondition. Do not change your dose or stop taking Aciphex unless you talk to your doctor. Take Aciphex for as long as it is prescribed even if you feel better.
• Aciphex is usually taken 1 time each day. Your doctor will tell you the time of day to take Aciphex, based on your medical condition.
• Aciphex can be taken with or withoutfood. Your doctor will tell you whether to take this medicine with or without food based on your medical condition.
• Swallow each Aciphextabletwhole. Do not chew, crush, or split Aciphex tablets. Tell your doctor if you cannot swallow tablets whole.
• If you miss a dose of Aciphex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your normal schedule. Do not take 2 doses at the same time.
• If you take too much Aciphex, call your doctor or yourpoison control centerat 1-800-222-1222 right away, or go to the nearesthospitalemergency room.
• Your doctor may prescribeantibioticmedicines with Aciphex to help treat a stomachinfectionand heal stomach (duodenal) ulcers that are caused bybacteriacalled H. pylori. Make sure you read thepatientinformation that comes with an antibiotic before you start taking it.