Definition of Checkpoint

Reviewed on6/3/2021

Checkpoint:A surveillance system responsible for monitoring the proper completion of aneventwithin acell. Cells contain a number of such systems. When a检查点system detects the failure of an event, it signals and calls for the inhibition of events downstream to the failure. These surveillance systems are termed checkpoints because they represent stagesinthecell cycle的细胞检查certain it is okay to proceed. Checkpointscontrolthe order and timing of cell cycle transitions and ensure that critical events, such asDNAreplicationandchromosomesegregation, are completed with high fidelity.

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